Intracytoplasmic sperm injection (ICSI) is an advanced fertility technique in which a single sperm is directly injected into an egg to achieve fertilization. It is primarily used for severe male-factor infertility or when standard IVF fertilization has previously failed, significantly improving fertilization rates.
Recommended when male-factor infertility is significant, when sperm is surgically retrieved, or when previous IVF cycles resulted in poor or failed fertilization.